Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817716 | 0.84 | DNM1 (0.44) | DNM1CA1CA2CA12CA9 | |
| Hydrochloric Acid SCHEMBL22729345 | 0.82 | DNM1 (0.43) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL10201790 | 0.81 | DNM1 (0.44) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL21197493 | 0.81 | DNM1 (0.42) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL22334966 | 0.81 | DNM1 (0.42) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL16589743 | 0.81 | DNM1 (0.42) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL24670688 | 0.79 | DNM1 (0.49) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL8191038 | 0.79 | DNM1 (0.41) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL2783100 | 0.78 | SETD7 (0.44) | DNM1CA1CA2CA12CA9 | |
| SCHEMBL14108219 | 0.78 | DNM1 (0.42) | DNM1CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952206-A1 | PROPHYLACTIC OR THERAPEUTIC DRUG FOR CONSTIPATION | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-12-09 | — | — | EP | disclosed |