Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 3/20 | 0.62 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.62 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.62 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26972786 | 0.81 | TRPM2 (0.63) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL29353177 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL22570313 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL29548995 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL19997378 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL18134682 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL21196515 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL21067521 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL18137037 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 | |
| Adenosine Diphosphate Ribose SCHEMBL14613247 | 0.77 | TRPM2 (1.00) | TRPM2MACROD2SIRT6MACROD1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9599606-B2 | ADP-ribose detection reagents | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150355172-A1 | ADP-RIBOSE DETECTION REAGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-12-10 | — | — | US | disclosed |