Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5481823 | 0.99 | PTGDR2 (0.40) | PTGDR2F2RMEN1KMT2ATHRA | |
| Trifluoroacetic Acid SCHEMBL1731674 | 0.96 | PTGDR2 (0.38) | PTGDR2F2RMEN1KMT2ATHRA | |
| Bromide SCHEMBL1729755 | 0.91 | THRA (0.39) | PTGDR2F2RMEN1KMT2ATHRA | |
| SCHEMBL1729531 | 0.89 | F2R (0.38) | F2RTHRATHRBKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1729541 | 0.89 | PTGDR2 (0.41) | PTGDR2F2RMEN1KMT2ATHRA | |
| Bromide SCHEMBL5490645 | 0.88 | F2R (0.39) | F2RTHRATHRBKDM4EMAPT | |
| SCHEMBL1731680 | 0.88 | F2R (0.35) | F2RTHRATHRBKDM4EMAPT | |
| Bromide SCHEMBL7612595 | 0.88 | F2R (0.46) | F2RMEN1KMT2AKDM4EMAPT | |
| Bromide SCHEMBL1729677 | 0.86 | F2R (0.46) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL5482791 | 0.86 | F2R (0.43) | F2RMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |