Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13282706 | 1.00 | CHRM3 (0.63) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL5741549 | 0.86 | CHRM3 (0.66) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL19049351 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL17294778 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL17301741 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL17294779 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL17294693 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL17294694 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL17294695 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRNA7BCHE | |
| SCHEMBL2482949 | 0.84 | CHRM3 (0.63) | CHRM3CHRM2CHRM1CHRNA7BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015185649-A9 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-01-05 | — | — | WO | disclosed |
| WO-2015185649-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-12-10 | — | — | WO | disclosed |