Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.94 |
| ▸ | ATM | Q13315 | 2/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5940935 | 0.97 | TRPA1 (1.00) | TRPA1ATMALDH1A1HSD17B10MAPT | |
| SCHEMBL29622820 | 0.97 | — | — | |
| SCHEMBL3498 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL7070510 | 0.94 | TRPA1 (0.94) | TRPA1ATMALDH1A1HSD17B10MAPT | |
| Methyl Alcohol SCHEMBL6064777 | 0.94 | TRPA1 (0.94) | TRPA1ATMALDH1A1HSD17B10MAPT | |
| SCHEMBL11303423 | 0.94 | TRPA1 (0.94) | TRPA1ATMALDH1A1HSD17B10MAPT | |
| Hydrogen Sulfide SCHEMBL11763650 | 0.94 | TRPA1 (0.94) | TRPA1ATMALDH1A1HSD17B10MAPT | |
| Ammonia Solution, Strong SCHEMBL3744582 | 0.94 | TRPA1 (0.94) | TRPA1ATMALDH1A1HSD17B10MAPT | |
| Phosphine SCHEMBL18662384 | 0.94 | TRPA1 (0.94) | TRPA1ATMALDH1A1HSD17B10MAPT | |
| SCHEMBL5658340 | 0.94 | TRPA1 (0.94) | TRPA1ATMALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088013-A | Device for monitoring food freshness and method of use thereof | 祖尔·格兰恩威茨 | 2019-08-02 | — | — | CN | disclosed |
| CN-106659756-A | Method for producing gel containing GNRH | 杰碧斯联合动物健康第二有限责任公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104250239-B | The polycyclic carboxylic acid derivates of fragrance | 山东轩竹医药科技有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-104250239-A | Aromatic polycyclic carboxylic acid derivative | KBP BIOSCIENCES CO LTD | 2014-12-31 | — | — | CN | disclosed |
| CN-101500583-B | Drug delivery polymers containing clindamycin hydrochloride | CONTROLLED THERAPEUTICS SCT | 2012-05-23 | — | — | CN | disclosed |
| EP-1791420-B1 | INDICATOR GRANULAR MATERIAL | MARS INC (US) | 2011-11-23 | — | — | EP | disclosed |
| CN-102076504-A | Temporary tattoo decals for detecting the presence of an analyte | KIMBERLY CLARK CO | 2011-05-25 | — | — | CN | disclosed |
| US-7670845-B2 | Indicator granular material | MARS INCORPORATED (US) | 2010-03-02 | — | — | US | disclosed |
| CN-101500583-A | Drug delivery polymer with hydrochloride salt of clindamycin | CONTROLLED THERAPEUTICS SCT (GB) | 2009-08-05 | — | — | CN | disclosed |
| US-20090181466-A1 | INDICATOR GRANULAR MATERIAL | MARS, INC. | 2009-07-16 | — | — | US | disclosed |
| EP-1791420-A1 | INDICATOR GRANULAR MATERIAL | Mars, Incorporated (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006032353-A1 | INDICATOR GRANULAR MATERIAL | MARS INCORPORATED (US) | 2006-03-30 | — | — | WO | disclosed |