Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K20 | Q9NYL2 | 4/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.54 |
| ▸ | CSK | P41240 | 3/20 | 0.54 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | KIT | P10721 | 2/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 7/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | BRAF | P15056 | 4/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | LYN | P07948 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | YES1 | P07947 | 1/20 | 0.47 |
| ▸ | HCK | P08631 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15860000 | 0.93 | BRAF (0.58) | MAP3K20MAPK14MAP3K7CSKMAP4K2 | |
| SCHEMBL17324206 | 0.93 | KIT (0.53) | MAP3K20MAPK14MAP3K7CSKMAP4K2 | |
| SCHEMBL18403089 | 0.90 | MAPK14 (0.52) | MAP3K20MAPK14MAP3K7CSKMAP4K2 | |
| SCHEMBL17321349 | 0.89 | ABL1 (0.60) | MAP3K20MAPK14MAP3K7CSKMAP4K2 | |
| SCHEMBL17324210 | 0.89 | CSK (0.59) | MAP3K20MAPK14MAP3K7CSKMAP4K2 | |
| SCHEMBL17313594 | 0.89 | CSK (0.59) | MAP3K20MAPK14MAP3K7CSKMAP4K2 | |
| SCHEMBL15859992 | 0.86 | BRAF (0.59) | KITABL1EGFRBRAFPDGFRA | |
| SCHEMBL15859952 | 0.86 | BRAF (0.59) | KITABL1EGFRBRAFPDGFRA | |
| SCHEMBL15860030 | 0.86 | ABL1 (0.56) | MAP3K20MAPK14ABL1EGFRBRAF | |
| SCHEMBL15860029 | 0.84 | KIT (0.51) | MAP3K20MAPK14MAP3K7CSKMAP4K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550772-B2 | Azaindole derivatives as multi kinase inhibitors | ORIBASE PHARMA (FR) | 2017-01-24 | — | — | US | disclosed |
| US-20150353539-A1 | AZAINDOLE DERIVATIVES AS MULTI KINASE INHIBITORS | ORIBASE PHARMA (FR) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353539-A1 | AZAINDOLE DERIVATIVES AS MULTI KINASE INHIBITORS | MAP2K2, MAP2K5, MAP2K3 | MAP3K20 11/4885MAPK14 143/4885MAP3K7 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.