Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 18/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5484759 | 0.92 | F2R (0.57) | F2RLMNAMAPTNPSR1 | |
| SCHEMBL6544325 | 0.89 | F2R (0.61) | F2RLMNAMAPT | |
| Bromide SCHEMBL1732831 | 0.87 | F2R (0.54) | F2R | |
| Trifluoroacetic Acid SCHEMBL5483379 | 0.86 | F2R (0.52) | F2R | |
| Bromide SCHEMBL1732231 | 0.83 | F2R (0.63) | F2R | |
| Bromide SCHEMBL1730340 | 0.83 | F2R (0.68) | F2RLMNAMAPT | |
| Bromide SCHEMBL1730048 | 0.83 | F2R (0.59) | F2RLMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL1729164 | 0.82 | F2R (0.65) | F2R | |
| SCHEMBL1729685 | 0.82 | F2R (0.82) | F2RLMNAMAPTNPSR1 | |
| Trifluoroacetic Acid SCHEMBL5483149 | 0.82 | F2R (0.77) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |