SCHEMBL6544325

SCHEMBL6544325

CCOc1cc2c(nc1C(=O)O)C(=N)N(CC(=O)c1cc(N3CCC(OC)CC3)c(OC)c(C(C)(C)C)c1)C2

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2R P25116 19/20 0.61
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1730482 0.92 F2R (0.60) F2R
Trifluoroacetic Acid SCHEMBL1729495 0.91 F2R (0.57) F2R
SCHEMBL1732428 0.89 F2R (0.57) F2RLMNAMAPT
Bromide SCHEMBL1732679 0.86 F2R (0.57) F2R
Bromide SCHEMBL1730340 0.85 F2R (0.68) F2RLMNAMAPT
SCHEMBL1729165 0.85 F2R (0.57) F2R
Bromide SCHEMBL1730336 0.85 F2R (0.56) F2R
Trifluoroacetic Acid SCHEMBL1729164 0.85 F2R (0.65) F2R
Bromide SCHEMBL1729919 0.85 F2R (0.58) F2R
Bromide SCHEMBL1730048 0.84 F2R (0.59) F2RLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391451-A1 2-IMINOPYRROLIDINE DERIVATES Eisai Co., Ltd. (JP) 2004-02-25 EP disclosed