Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | KDM1A | O60341 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539196 | 1.00 | MAOA (0.61) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL29785655 | 1.00 | MAOA (0.61) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL801282 | 0.90 | MAOA (0.52) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL13280435 | 0.90 | MAOA (0.55) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL662711 | 0.89 | MAOA (0.57) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| Hydrochloric Acid SCHEMBL4799055 | 0.87 | MAOA (0.55) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL31706160 | 0.85 | MAOA (0.54) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL14862724 | 0.85 | MAOA (0.54) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL5863593 | 0.84 | HPGD (0.55) | MAOAMAOBKDM1ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16464069 | 0.84 | MAOA (0.53) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703098-B2 | Labelled adrenomedullin derivatives and their use for imaging and therapy | INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) | 2014-04-22 | — | — | US | claimed |
| US-8475764-B2 | Labelled adrenomedullin derivatives and their use for imaging and therapy | INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) | 2013-07-02 | — | — | US | claimed |
| US-20080274050-A1 | Labelled Adrenomedullin Derivatives and Their Use for Imaging and Therapy | INSTITUT DE CARDIOLOGIE DE MONTRÉAL (CA) | 2008-11-06 | — | — | US | claimed |
| US-20150246145-A1 | Labelled adrenomedullin derivatives and their use for imaging and therapy. | PULMOSCIENCE INC (CA) | 2015-09-03 | — | — | US | disclosed |
| US-9062123-B2 | Labelled adrenomedullin derivatives and their use for imaging and therapy | PLUMOSCIENCE INC. (CA) | 2015-06-23 | — | — | US | disclosed |
| US-8703098-B2 | Labelled adrenomedullin derivatives and their use for imaging and therapy | INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) | 2014-04-22 | — | — | US | disclosed |
| US-8475764-B2 | Labelled adrenomedullin derivatives and their use for imaging and therapy | INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) | 2013-07-02 | — | — | US | disclosed |
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20080274050-A1 | Labelled Adrenomedullin Derivatives and Their Use for Imaging and Therapy | INSTITUT DE CARDIOLOGIE DE MONTRÉAL (CA) | 2008-11-06 | — | — | US | disclosed |