Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19079629 | 0.88 | MAPT (0.47) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL20582014 | 0.87 | MAPT (0.49) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL3334421 | 0.87 | MAPT (0.49) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL3336043 | 0.87 | MAPT (0.49) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL13621251 | 0.87 | MAPT (0.49) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL16500346 | 0.87 | MAPT (0.49) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL16500298 | 0.87 | MAPT (0.49) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL23104821 | 0.85 | TLR4 (0.46) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL21137974 | 0.85 | TLR4 (0.46) | MAPTTLR4CA12CA1CA2 | |
| SCHEMBL22107783 | 0.83 | MAPT (0.46) | MAPTTLR4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015186114-A1 | NICOTINAMIDE RIBOSIDE ANALOGS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-12-10 | — | — | WO | disclosed |