Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5483274 | 0.99 | F2R (0.52) | F2RACHEMAPTKDM4ERAB9A | |
| Bromide SCHEMBL1732738 | 0.86 | F2R (0.60) | F2RACHEMAPTKDM4ERAB9A | |
| Bromide SCHEMBL1732082 | 0.84 | F2R (0.52) | F2RMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL6544923 | 0.84 | F2R (0.51) | F2RMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL1730455 | 0.83 | F2R (0.61) | F2RMAPTKDM4ERAB9ANPC1 | |
| Bromide SCHEMBL1730552 | 0.82 | F2R (0.61) | F2RMAPTKDM4ERAB9ANPC1 | |
| Bromide SCHEMBL1732047 | 0.82 | F2R (0.50) | F2RMAPTKDM4ERAB9ANPC1 | |
| Bromide SCHEMBL5488062 | 0.81 | F2R (0.55) | F2RMAPTKDM4ERAB9ANPC1 | |
| Bromide SCHEMBL1729970 | 0.81 | F2R (0.49) | F2RMAPTKDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL1729446 | 0.80 | F2R (0.58) | F2RMAPTKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |