Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 14/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 14/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956249 | 0.91 | CSNK1D (0.45) | CSNK1DCSNK1ERIPK1 | |
| SCHEMBL17328326 | 0.91 | CSNK1D (0.42) | CSNK1DCSNK1EDHODHRXFP1RIPK1 | |
| SCHEMBL9956875 | 0.90 | CSNK1D (0.47) | CSNK1DCSNK1EDHODHRXFP1RIPK1 | |
| SCHEMBL9956902 | 0.90 | RIPK1 (0.40) | CSNK1DCSNK1ETGFBR1RXFP1RIPK1 | |
| SCHEMBL9957183 | 0.90 | CSNK1D (0.46) | CSNK1DCSNK1E | |
| SCHEMBL9956268 | 0.89 | CSNK1D (0.42) | CSNK1DCSNK1ERXFP1RIPK1 | |
| SCHEMBL9955410 | 0.89 | CSNK1D (0.41) | CSNK1DCSNK1EDHODHRXFP1 | |
| SCHEMBL9957288 | 0.88 | CSNK1D (0.39) | CSNK1DCSNK1EDHODHTGFBR1RXFP1 | |
| SCHEMBL9955708 | 0.88 | CSNK1D (0.38) | CSNK1DCSNK1ERXFP1RIPK1 | |
| SCHEMBL9956511 | 0.88 | CSNK1D (0.38) | CSNK1DCSNK1ERXFP1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635578-B1 | 2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES | HENGRUI USA LTD (US) | 2015-12-16 | — | — | EP | claimed |