Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1732567 | 1.00 | MEN1 (0.35) | MEN1CYP1A2KMT2AALDH1A1THRB | |
| SCHEMBL1036503 | 1.00 | MEN1 (0.35) | MEN1CYP1A2KMT2AALDH1A1THRB | |
| SCHEMBL10412072 | 0.90 | HDAC1 (0.36) | MEN1CYP1A2KMT2AALDH1A1THRB | |
| SCHEMBL6045545 | 0.86 | PPARD (0.38) | MEN1KMT2AALDH1A1TDP1LCK | |
| SCHEMBL6045650 | 0.84 | PPARD (0.41) | MEN1KMT2AALDH1A1TDP1LCK | |
| SCHEMBL1449044 | 0.84 | — | — | |
| SCHEMBL28392031 | 0.83 | MEN1 (0.34) | MEN1CYP1A2KMT2AALDH1A1THRB | |
| SCHEMBL11156087 | 0.82 | PPARD (0.44) | MEN1KMT2AALDH1A1TDP1LCK | |
| SCHEMBL6931988 | 0.82 | PPARD (0.44) | MEN1KMT2AALDH1A1TDP1LCK | |
| SCHEMBL7776233 | 0.82 | PPARD (0.44) | MEN1KMT2AALDH1A1TDP1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852433-B1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZERIA PHARM CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |