Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1732640 | 0.91 | F2R (0.62) | F2RALDH1A1GAAMAPTKDM4E | |
| SCHEMBL14449141 | 0.85 | F2R (0.72) | F2RALDH1A1GAAMAPTLMNA | |
| SCHEMBL1730562 | 0.85 | F2R (0.57) | F2R | |
| Bromide SCHEMBL1729239 | 0.84 | F2R (0.73) | F2RALDH1A1GAAMAPTKDM4E | |
| SCHEMBL6544923 | 0.84 | F2R (0.51) | F2RALDH1A1GAAMAPTKDM4E | |
| SCHEMBL14449044 | 0.82 | F2R (0.71) | F2R | |
| Bromide SCHEMBL5484851 | 0.82 | F2R (0.76) | F2RALDH1A1GAAMAPTKDM4E | |
| SCHEMBL1730455 | 0.82 | F2R (0.61) | F2RALDH1A1GAAMAPTKDM4E | |
| Bromide SCHEMBL1730903 | 0.82 | F2R (0.69) | F2RALDH1A1GAAMAPTKDM4E | |
| Bromide SCHEMBL1730448 | 0.82 | F2R (0.71) | F2RMAPTKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852433-B1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZERIA PHARM CO LTD (JP) | 2011-11-23 | — | — | EP | claimed |
| EP-1852433-B1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZERIA PHARM CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |