Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 6/20 | 0.66 |
| ▸ | CASP3 | P42574 | 6/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | CCR6 | P51684 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17328940 | 1.00 | TERT (0.66) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328933 | 0.92 | TERT (0.65) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328931 | 0.92 | TERT (0.65) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328973 | 0.91 | TERT (0.65) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328919 | 0.91 | TERT (0.65) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328915 | 0.89 | NR4A1 (0.72) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328912 | 0.89 | NR4A1 (0.72) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328905 | 0.88 | NR4A1 (0.66) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL20173 | 0.87 | TERT (0.64) | TERTNR4A1CASP3PTPN1CASP1 | |
| SCHEMBL17328918 | 0.87 | TERT (0.64) | TERTNR4A1CASP3PTPN1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609108-B1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | SUZHOU NEUPHARMA CO LTD (CN) | 2015-12-16 | — | — | EP | claimed |