Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 7/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.73 |
| ▸ | CASP1 | P29466 | 1/20 | 0.73 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | TERT | O14746 | 4/20 | 0.71 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.69 |
| ▸ | CASP3 | P42574 | 2/20 | 0.69 |
| ▸ | CDC37 | Q16543 | 2/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | CCR6 | P51684 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17328948 | 1.00 | NR4A1 (0.73) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL19759 | 1.00 | NR4A1 (0.73) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328951 | 1.00 | NR4A1 (0.73) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328939 | 0.91 | NR4A1 (0.71) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328943 | 0.91 | NR4A1 (0.71) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328915 | 0.91 | NR4A1 (0.72) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328912 | 0.91 | NR4A1 (0.72) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328914 | 0.89 | TERT (0.71) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328910 | 0.89 | TERT (0.71) | NR4A1PTPN1CASP1ABHD6KDM4E | |
| SCHEMBL17328937 | 0.89 | TERT (0.71) | NR4A1PTPN1CASP1ABHD6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609108-B1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | SUZHOU NEUPHARMA CO LTD (CN) | 2015-12-16 | — | — | EP | disclosed |