Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17329378 | 0.88 | MAPT (0.43) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL17329383 | 0.80 | KDM4E (0.50) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL17365980 | 0.78 | POLB (0.41) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL17329362 | 0.77 | CXCR4 (0.68) | HTTCYP1A2KMT2APOLBCYP2D6 | |
| SCHEMBL20550090 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL14685203 | 0.72 | SMN1; SMN2 (0.57) | ALDH1A1HTTSMN1; SMN2MAPTKDM4E | |
| SCHEMBL20433804 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL17347580 | 0.67 | POLB (0.38) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL21912825 | 0.65 | MAPK1 (0.61) | ALDH1A1HTTMAPTCYP1A2MEN1 | |
| SCHEMBL28223149 | 0.64 | NPSR1 (0.50) | ALDH1A1HTTSMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960284-B1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |