1,2-Naphthoquinone

1,2-Naphthoquinone

SCHEMBL173316

O=C1C=Cc2ccccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 8/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
KDM4E B2RXH2 4/20 1.00
PTPN1 P18031 4/20 1.00
IDO1 P14902 3/20 1.00
CES1 P23141 3/20 1.00
MAPT P10636 3/20 1.00
LMNA P02545 2/20 1.00
BCHE P06276 2/20 1.00
POLB P06746 2/20 1.00
THRB P10828 2/20 1.00
RECQL P46063 2/20 1.00
ALDH1A1 P00352 2/20 1.00
HPGD P15428 2/20 1.00
PTPN22 Q9Y2R2 2/20 1.00
PKM P14618 1/20 1.00
ALOX15 P16050 1/20 1.00
ACHE P22303 1/20 1.00
HSD17B10 Q99714 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Naphthoquinone SCHEMBL29363665 1.00 PTPRC (1.00) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL15167712 1.00 PTPRC (1.00) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL30697786 0.98 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL28304516 0.98 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL27880766 0.98 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL28008660 0.98 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL28236061 0.98 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL27864137 0.98 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL30715501 0.98 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL9245768 0.95 PTPRC (0.91) PTPRCMEN1KMT2AKDM4EPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7863 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12523665-B2 In-field colour test for screening fentanyl and analogues thereof UNIVERSITY OF TECHNOLOGY SYDNEY (AU) 2026-01-13 US claimed
US-12476287-B2 Dual electrolyte approach for high voltage batteries URBAN ELECTRIC POWER INC. (US) 2025-11-18 US claimed
US-20250262169-A1 METHODS OF TREATING COENZYME Q10 DEFICIENCY THLIVERIS, ANDREW T. 2025-08-21 US claimed
EP-4602020-A1 ANTIPOLYMERANT COMPOSITIONS WITH NAPHTHOQUINONE AND HYDROXYLAMINE AND METHODS OF USING Ecolab USA, Inc. (US) 2025-08-20 EP claimed
EP-3777852-B1 PHARMACEUTICAL COMPOSITION INCLUDING 1,2-NAPHTHOQUINONE DERIVATIVE COMPOUND FOR PREVENTION OR TREATMENT OF SOLID CANCERS OR BLOOD CANCERS YUNGJIN PHARMACEUTICAL CO LTD (KR) 2025-07-02 EP claimed
WO-2025109337-A1 DIRECT AIR CAPTURE SYSTEM CARBONBIT TECHNOLOGIES LIMITED (GB) 2025-05-30 WO claimed
CN-120015756-A Electrode plate, preparation method thereof, battery and power utilization device 浙江极氪智能科技有限公司 2025-05-16 CN claimed
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN claimed
CN-119873755-A Application of quinone compound as photocatalyst in photocatalytic hydrogen peroxide production 北京工业大学 2025-04-25 CN claimed
CN-119791112-A Application of naphthoquinone compound in preparation of nematode prevention and control medicament 贵州大学 2025-04-11 CN claimed
US-4111648-A REACTIVE DYEING SYSTEMS USING DYES WITH CARBOXYLIC ACID GROUPS BURLINGTON INDUSTRIES, INC. (US) 1978-09-05 US claimed
US-4112044-A CATALYTIC ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1978-09-05 US claimed
US-4103057-A SYNDIOTACTIC POLY(1,2-)BUTADIENE NIPPON PAINT COMPANY (JP) 1978-07-25 US claimed
US-4078048-A Process and apparatus for removing sulfur from stack gases in the form of elemental sulfur COMBUSTION EQUIPMENT ASSOCIATES, INC. (US) 1978-03-07 US claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-4069123-A ALKYL ACRYLATE OR METHACRYLATE HOMO- OR COPOLYMER WITH QUINONE TYPE ULTRAVIOLET SENSITIZER NATIONAL STARCH & CHEMICAL CORPORATION (US) 1978-01-17 US claimed
US-4049769-A Separation of uranium isotopes by accelerated isotope exchange reactions ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1977-09-20 US claimed
US-4005055-A Anaerobic aminimide curing compositions SKEIST LABORATORIES, INCORPORATED (US) 1977-01-25 US claimed
US-3948667-A HOMO- AND CO-POLYMERS OF CYCLIZED BUTADIENE AND A CROSSLINKING AGENT JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) 1976-04-06 US claimed
US-3941759-A A QUINONE PHOTOSENSITIZER AND A TRANSITION METAL DIALKYL-DITHIOCARBAMATE OWENS-ILLINOIS, INC. (US) 1976-03-02 US claimed