1,2-Naphthoquinone

1,2-Naphthoquinone

SCHEMBL30715501

O=C1C=Cc2ccccc2C1=O.[K]

nearest known ligand 0.95

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 8/20 0.95
MEN1 O00255 4/20 0.95
KMT2A Q03164 4/20 0.95
KDM4E B2RXH2 4/20 0.95
PTPN1 P18031 4/20 0.95
IDO1 P14902 3/20 0.95
CES1 P23141 3/20 0.95
MAPT P10636 3/20 0.95
LMNA P02545 2/20 0.95
BCHE P06276 2/20 0.95
POLB P06746 2/20 0.95
THRB P10828 2/20 0.95
RECQL P46063 2/20 0.95
ALDH1A1 P00352 2/20 0.95
HPGD P15428 2/20 0.95
PTPN22 Q9Y2R2 2/20 0.95
PKM P14618 1/20 0.95
ALOX15 P16050 1/20 0.95
ACHE P22303 1/20 0.95
HSD17B10 Q99714 1/20 0.95

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Naphthoquinone SCHEMBL29363665 0.98 PTPRC (1.00) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL15167712 0.98 PTPRC (1.00) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL173316 0.98 PTPRC (1.00) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL30697786 0.95 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL28304516 0.95 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL28008660 0.95 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL27864137 0.95 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL28236061 0.95 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL27880766 0.95 PTPRC (0.95) PTPRCMEN1KMT2AKDM4EPTPN1
1,2-Naphthoquinone SCHEMBL9245768 0.93 PTPRC (0.91) PTPRCMEN1KMT2AKDM4EPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250147230-A1 OPTICAL FIBER AND METHOD FOR MANUFACTURING OPTICAL FIBER FURUKAWA ELECTRIC CO., LTD. (JP) 2025-05-08 US disclosed
WO-2024162068-A1 OPTICAL FIBER AND METHOD FOR MANUFACTURING OPTICAL FIBER 古河電気工業株式会社 2024-08-08 WO disclosed