⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954643 | 0.98 | CES2 (0.48) | — | |
| SCHEMBL10953427 | 0.98 | CES2 (0.48) | — | |
| SCHEMBL10702206 | 0.98 | CES2 (0.48) | — | |
| SCHEMBL10704056 | 0.98 | CES2 (0.48) | — | |
| SCHEMBL10704481 | 0.98 | CES2 (0.48) | — | |
| SCHEMBL2097337 | 0.98 | CES2 (0.48) | — | |
| SCHEMBL9802054 | 0.98 | CES2 (0.48) | — | |
| SCHEMBL1145474 | 0.92 | — | — | |
| SCHEMBL23174998 | 0.90 | — | — | |
| SCHEMBL9644539 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049664-A | Antitumor agents | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-09-17 | — | — | US | claimed |
| EP-0135444-A1 | Pyroglumatic derivatives, process for their preparation , intermediates and bactericidal and/or fungicidal cosmetic or pharmaceutical compositions | LABORATOIRES SEROBIOLOGIQUES S.A. (FR) | 1985-03-27 | — | — | EP | claimed |
| US-4361514-A | Carbon analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1982-11-30 | — | — | US | claimed |
| US-4282149-A | Carbon and oxygen analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1981-08-04 | — | — | US | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| EP-4282411-A1 | LIPOYL-GLU-ALA FOR THE TREATMENT OF NEURODEGENERATIVE DAMAGE CAUSED BY TRAUMATIC BRAIN INJURY | Ischemix LLC (US) | 2023-11-29 | — | — | EP | disclosed |
| EP-3615023-B1 | LIPOYL-GLU-ALA FOR THE TREATMENT OF NEURODEGENERATIVE DAMAGE CAUSED BY TRAUMATIC BRAIN INJURY | ISCHEMIX LLC (US) | 2023-06-21 | — | — | EP | disclosed |
| US-11213509-B2 | Compositions and methods for treating traumatic brain injury | Ischemix, LLC (US) | 2022-01-04 | — | — | US | disclosed |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-10-07 | — | — | US | disclosed |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-09-07 | — | — | US | disclosed |
| EP-3828176-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-20200352904-A1 | Compositions And Methods For Treating Traumatic Brain Injury | ISCHEMIX LLC | 2020-11-12 | — | — | US | disclosed |
| WO-1995035308-A1 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1995-12-28 | — | — | WO | disclosed |
| WO-1995034540-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-12-21 | — | — | WO | disclosed |
| US-5049664-A | Antitumor agents | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0356154-A2 | Trehalose derivatives | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0135444-A1 | Pyroglumatic derivatives, process for their preparation , intermediates and bactericidal and/or fungicidal cosmetic or pharmaceutical compositions | LABORATOIRES SEROBIOLOGIQUES S.A. (FR) | 1985-03-27 | — | — | EP | disclosed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | disclosed |
| US-4159984-A | METAL AND PROTON DONOR | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-3966768-A | Substituted 1,3-dioxepins | THE DOW CHEMICAL COMPANY (US) | 1976-06-29 | — | — | US | disclosed |