Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1732885 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP2D6GRM2GRM3MEN1 | |
| SCHEMBL1000119 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP2D6GRM2GRM3MEN1 | |
| SCHEMBL28392033 | 0.83 | GRM2 (0.31) | CYP1A2GRM2GRM3MEN1KMT2A | |
| Ibrotamide SCHEMBL1641878 | 0.78 | EPHX1 (0.31) | — | |
| SCHEMBL2730980 | 0.73 | — | — | |
| SCHEMBL31430102 | 0.72 | SLC22A6 (0.31) | CYP1A2MEN1KMT2AALDH1A1THRB | |
| SCHEMBL9952000 | 0.69 | ALDH1A1 (0.33) | CYP1A2CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL3922345 | 0.69 | ALDH1A1 (0.33) | CYP1A2CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL2303259 | 0.69 | ALDH1A1 (0.33) | CYP1A2CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL2233286 | 0.69 | ALDH1A1 (0.33) | CYP1A2CYP2D6MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852433-B1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZERIA PHARM CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |