SCHEMBL1733341

SCHEMBL1733341

C=CCC(C)(C)c1ccccc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 7/20 0.45
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.42
ALOX15 P16050 3/20 0.42
MAPT P10636 2/20 0.41
CYP3A4 P08684 2/20 0.39
KDM4E B2RXH2 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
HMGB1 P09429 1/20 0.37
HPGD P15428 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
NAPRT Q6XQN6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22230533 0.85 ALDH1A1 (0.43) KMT2AALDH1A1TSHRSMN1; SMN2MEN1
SCHEMBL247594 0.80 ALDH1A1 (0.50) ALDH1A1TSHRSMN1; SMN2ALOX15MAPT
SCHEMBL2718019 0.80 ALDH1A1 (0.62) KMT2AALDH1A1TSHRSMN1; SMN2MEN1
SCHEMBL11180581 0.79 ALDH1A1 (0.48) ALDH1A1TSHRSMN1; SMN2ALOX15MAPT
SCHEMBL3307441 0.79 ALDH1A1 (0.48) ALDH1A1TSHRSMN1; SMN2ALOX15MAPT
SCHEMBL2574987 0.77 TAAR1 (0.48) ALDH1A1TSHRSMN1; SMN2HTTALOX15
SCHEMBL28284391 0.77 ALDH1A1 (0.46) ALDH1A1TSHRSMN1; SMN2ALOX15MAPT
Acrylic Acid SCHEMBL27869579 0.76 ALDH1A1 (0.45) KMT2AALDH1A1TSHRSMN1; SMN2ALOX15
SCHEMBL11437771 0.75 ALDH1A1 (0.52) KMT2AALDH1A1TSHRSMN1; SMN2MEN1
SCHEMBL15209498 0.75 ALDH1A1 (0.43) KMT2AALDH1A1TSHRSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902077-B2 NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD OREAL (FR) 2018-07-18 EP claimed
EP-1902077-B1 NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD OREAL (FR) 2011-11-16 EP claimed
WO-2011133072-A1 ARRANGEMENT FOR OPERATING A HYDRAULIC DEVICE PARKER HANNIFIN AB (SE) 2011-10-27 WO claimed
EP-1043343-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-1043345-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-1043344-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-1043347-B1 Cosmetic composition containing star shaped polymers and their use OREAL (FR) 2003-09-03 EP claimed
EP-0897298-B1 COSMETIC AEROSOL FIXATIVE COMPOSITION PROVIDING SHINE, AND METHODS OREAL (FR) 2003-03-26 EP claimed
EP-1043346-B1 Cosmetic compositions containing star shaped polymers and their use in particular for hair OREAL (FR) 2003-03-05 EP claimed
EP-0815848-B1 Use in cosmetics of copolymers with a flexible backbone, grafted with hydrophobic and rigid macromonomers; compositions using same OREAL (FR) 2000-01-26 EP claimed
EP-0764436-B1 Aqueous cosmetic or dermatological composition comprising a filmogenic oligomer and rigid, non-filmforming nanoparticles; uses OREAL (FR) 1999-02-24 EP claimed
EP-0774248-B1 Keratinous fiber treating composition containing at least a binding polymer and at least a ceramide-type compound and methods OREAL (FR) 1999-02-10 EP claimed
EP-3781574-A1 MACROCYCLIC SPIROETHERS AS MCL-1 INHIBITORS Ascentage Pharma (Suzhou) Co., Ltd. (CN) 2021-02-24 EP disclosed
WO-2020147802-A1 MACROCYCLIC SPIROETHERS AS MCL-1 INHIBITORS ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) 2020-07-23 WO disclosed
EP-1889890-B2 Method for applying a polyvinyl ester dispersion adhesive using a jet and use of polyvinyl ester dispersion adhesives CELANESE EMULSIONS GMBH (DE) 2014-06-18 EP disclosed
EP-1889890-B1 Method for applying a polyvinyl ester dispersion adhesive using a jet and use of polyvinyl ester dispersion adhesives CELANESE EMULSIONS GMBH (DE) 2010-01-27 EP disclosed
EP-1889890-A1 Method for applying a polyvinyl ester dispersion adhesive using a jet and use of polyvinyl ester dispersion adhesives Celanese Emulsions GmbH (DE) 2008-02-20 EP disclosed
EP-0969063-B1 Adhesive compositions for use in package encapsulant compositions for electronic devices NAT STARCH CHEM INVEST (US) 2007-04-11 EP disclosed
EP-0969063-A2 Package encapsulant compositions for use in electronic devices National Starch and Chemical Investment Holding Corporation (US) 2000-01-05 EP disclosed
EP-0969058-A2 Method of making encapsulated electronic component with reworkable package encapsulants National Starch and Chemical Investment Holding Corporation (US) 2000-01-05 EP disclosed