SCHEMBL17334223

SCHEMBL17334223

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nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17334222 0.84 GAA (0.40) GAA
SCHEMBL23113093 0.82 ALDH1A1 (0.35)
SCHEMBL17574069 0.75 GAA (0.48) GAA
SCHEMBL13548866 0.73 GAA (0.46) GAA
SCHEMBL9627444 0.73 GAA (0.46) GAA
SCHEMBL10456471 0.72 GAA (0.50) GAA
SCHEMBL9138775 0.72 GAA (0.56) GAA
SCHEMBL29090047 0.70
SCHEMBL66105 0.70
SCHEMBL4110980 0.70 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10246474-B2 Preparation of a hydroxyalkyl phosphonic acid ROHM AND HAAS COMPANY (US) 2019-04-02 US claimed
EP-2957564-B1 PREPARATION OF A HYDROXYALKYL PHOSPHONIC ACID ROHM & HAAS (US) 2018-09-12 EP claimed
EP-2957564-A1 PREPARATION OF A HYDROXYALKYL PHOSPHONIC ACID Rohm and Haas Company (US) 2015-12-23 EP claimed
US-20150361117-A1 PREPARATION OF A HYDROXYALKYL PHOSPHONIC ACID ROHM AND HAAS COMPANY 2015-12-17 US claimed
US-10246474-B2 Preparation of a hydroxyalkyl phosphonic acid ROHM AND HAAS COMPANY (US) 2019-04-02 US disclosed
EP-2957564-B1 PREPARATION OF A HYDROXYALKYL PHOSPHONIC ACID ROHM & HAAS (US) 2018-09-12 EP disclosed
EP-2957564-A1 PREPARATION OF A HYDROXYALKYL PHOSPHONIC ACID Rohm and Haas Company (US) 2015-12-23 EP disclosed
US-20150361117-A1 PREPARATION OF A HYDROXYALKYL PHOSPHONIC ACID ROHM AND HAAS COMPANY 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10246474-B2 Preparation of a hydroxyalkyl phosphonic acid PHOSPHO1, PIK3CA, PHPT1 GAA 825/4885
US-20150361117-A1 PREPARATION OF A HYDROXYALKYL PHOSPHONIC ACID PHOSPHO1, PIK3CA, PHPT1 GAA 825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.