Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17337242 | 0.90 | PRKCZ (0.34) | PRKCZTSHRCNR2 | |
| SCHEMBL9953131 | 0.84 | TAAR1 (0.31) | RORC | |
| SCHEMBL14742439 | 0.83 | TSHR (0.32) | PRKCZTSHR | |
| SCHEMBL17332912 | 0.80 | PRKCZ (0.35) | PRKCZCNR2 | |
| SCHEMBL23065012 | 0.79 | PRKCZ (0.34) | PRKCZPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31711310 | 0.78 | PRKCZ (0.34) | PRKCZCNR2 | |
| SCHEMBL14736579 | 0.78 | PRKCZ (0.34) | PRKCZCNR2 | |
| SCHEMBL23074517 | 0.76 | PRKCZ (0.32) | PRKCZTSHRCNR2 | |
| SCHEMBL9953794 | 0.74 | TAAR1 (0.40) | — | |
| SCHEMBL14742339 | 0.73 | DHODH (0.33) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015191677-A1 | BICYCLIC HETEROARYLAMINOALKYL PHENYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2015-12-17 | — | — | WO | disclosed |