SCHEMBL1733746

SCHEMBL1733746

CC(COc1ccc(C(=O)c2ccccc2)c(O)c1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD209 Q9NNX6 2/20 0.52
TYR P14679 3/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
HPGD P15428 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
PGR P06401 1/20 0.45
CYP2D6 P10635 1/20 0.45
SLC6A2 P23975 1/20 0.45
PDE4A P27815 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
HRH1 P35367 1/20 0.45
HTT P42858 1/20 0.45
SLC6A3 Q01959 1/20 0.45
PDE4D Q08499 1/20 0.45
AKR1B1 P15121 1/20 0.44
DPP4 P27487 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30507746 0.87 HPGD (0.47) CD209NPC1RAB9AHPGDALDH1A1
SCHEMBL28382424 0.86 TYR (0.48) TYRNPC1RAB9A
SCHEMBL7754054 0.83 MAOB (0.55) CD209TYRNPC1RAB9AHPGD
SCHEMBL4652451 0.80 TYR (0.61) CD209TYRMAPK1
SCHEMBL28575758 0.75 TYR (0.44) TYR
SCHEMBL9391131 0.75 HPGD (0.41) CD209NPC1RAB9AHPGDALDH1A1
SCHEMBL24376194 0.75 HPGD (0.65) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL29969473 0.75 HPGD (0.65) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL8927808 0.75 HPGD (0.58) NPC1RAB9AHPGDALDH1A1LMNA
SCHEMBL940128 0.74 TYR (0.50) CD209TYRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2172185-B1 Cosmetic material comprising octyl hydroxy stearate oligomer PARAHERMOSA CO LTD (JP) 2011-11-23 EP claimed
WO-2024122465-A1 EMULSIFIED TOPICAL COMPOSITION AND METHOD FOR PRODUCING SAME ロート製薬株式会社 2024-06-13 WO disclosed
US-20240166823-A1 CROSSLINKED ORGANOSILICON RESIN, A METHOD FOR PRODUCING SAME, AND A COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-23 US disclosed
US-11912828-B2 Crosslinked organosilicon resin, a method for producing same, and a cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-27 US disclosed
US-20240009091-A1 OIL-IN-WATER-TYPE COSMETIC COMPOSITION KAO CORPORATION (JP) 2024-01-11 US disclosed
EP-4286015-A1 OIL-IN-WATER-TYPE EMULSION COSMETIC Kao Corporation (JP) 2023-12-06 EP disclosed
US-20210277187-A1 CROSSLINKED ORGANOSILICON RESIN, A METHOD FOR PRODUCING SAME, AND A COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-09-09 US disclosed
WO-2021153705-A1 EXTERNAL SKIN PREPARATION 花王株式会社 2021-08-05 WO disclosed
US-20210228754-A1 COMPOSITION, SPRAY, AND WIPER FUJIFILM CORPORATION (JP) 2021-07-29 US disclosed
EP-3822303-A1 CROSSLINKED ORGANOSILICON RESIN, METHOD FOR PRODUCING SAME, AND COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-19 EP disclosed
US-20100112017-A1 Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics DOW CORNING TORAY COMPANY, LTD. (JP) 2010-05-06 US disclosed
US-20100087551-A1 COSMETIC MATERIAL PARAHERMOSA CO., LTD. (JP) 2010-04-08 US disclosed
EP-2172185-A2 Cosmetic material comprising octyl hydroxy stearate oligomer Parahermosa Co., Ltd. (JP) 2010-04-07 EP disclosed
US-20100036062-A1 Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation DOW TORAY CO., LTD. (JP) 2010-02-11 US disclosed
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane DOW CORNING TORAY COMPANY, LTD. (JP) 2010-02-04 US disclosed
WO-2009084711-A1 METHOD OF PRODUCING AMINO ACID-MODIFIED ORGANOPOLYSILOXANE EMULSIONS DOW CORNING TORAY CO., LTD. (JP) 2009-07-09 WO disclosed
EP-2022812-A1 POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION Dow Corning Toray Co., Ltd. (JP) 2009-02-11 EP disclosed
WO-2008032883-A2 COMPOSITION FOR THE PREPARATION OF COSMETICS, COSMETIC, AND METHOD FOR THE PREPARATION OF WATER-CONTAINING COSMETICS DOW CORNING TORAY CO., LTD. (JP) 2008-03-20 WO disclosed
EP-1895979-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2008-03-12 EP disclosed
WO-2006137576-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2006-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210277187-A1 CROSSLINKED ORGANOSILICON RESIN, A METHOD FOR PRODUCING SAME, AND A COSMETIC F12, SCO2, H1-0 CD209 607/4885TYR 2078/4885NPC1 3531/4885
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane H1-0, H1-2, CHRM1 CD209 602/4885TYR 253/4885NPC1 3397/4885
US-20100112017-A1 Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics H1-0, DEGS1, MSR1 CD209 292/4885TYR 370/4885NPC1 1782/4885
US-20240166823-A1 CROSSLINKED ORGANOSILICON RESIN, A METHOD FOR PRODUCING SAME, AND A COSMETIC NOTUM, OR10J3, CUTA CD209 1086/4885TYR 282/4885NPC1 4189/4885
US-11912828-B2 Crosslinked organosilicon resin, a method for producing same, and a cosmetic NOTUM, OR10J3, CUTA CD209 1086/4885TYR 282/4885NPC1 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.