SCHEMBL1733756

SCHEMBL1733756

C1CCC1.CCN1CCN(c2cccc3c2C(=O)N([C@H](CCCNC(=O)O)c2ccc(OC)c(OC)c2)C3=O)CC1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1474864 0.90 UTS2R (0.65) UTS2R
SCHEMBL1472426 0.90 UTS2R (0.80) UTS2R
SCHEMBL1472430 0.90 UTS2R (0.80) UTS2R
SCHEMBL1733494 0.89 UTS2R (0.83) UTS2R
Cyclopentane SCHEMBL1734638 0.89 UTS2R (0.83) UTS2R
SCHEMBL1472550 0.87 UTS2R (0.69) UTS2R
SCHEMBL1472551 0.87 UTS2R (0.69) UTS2R
SCHEMBL1472269 0.86 UTS2R (0.77) UTS2R
SCHEMBL1472353 0.85 UTS2R (0.63) UTS2R
SCHEMBL1472357 0.85 UTS2R (0.63) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993554-B1 UROTENSIN II RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA NV (BE) 2011-11-23 EP claimed