Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696231 | 0.85 | FOLH1 (0.53) | FOLH1ALDH1A1TSHRGAASRC | |
| SCHEMBL27987619 | 0.77 | FOLH1 (0.45) | FOLH1MEN1KMT2AALDH1A1 | |
| SCHEMBL1919736 | 0.76 | PTGER4 (0.42) | FOLH1KMT2A | |
| SCHEMBL5021484 | 0.76 | CPN1 (0.46) | CPN1CPB2MEN1KMT2AALDH1A1 | |
| SCHEMBL288665 | 0.74 | AKR1C3 (0.49) | CPN1CPB2ALDH1A1GAA | |
| SCHEMBL27996917 | 0.74 | CPN1 (0.49) | CPN1CPB2MEN1KMT2AALDH1A1 | |
| SCHEMBL20522793 | 0.74 | FOLH1 (0.51) | FOLH1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21808436 | 0.74 | AKR1C3 (0.49) | CPN1CPB2ALDH1A1GAA | |
| SCHEMBL11369027 | 0.74 | FOLH1 (0.48) | FOLH1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10409409 | 0.73 | FOLH1 (0.57) | FOLH1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154956-A1 | GLUCAGON ANTAGONISTS | Ligand Pharmaceuticals, Inc. (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191900-A1 | GLUCAGON ANTAGONISTS | LIGAND PHARMACEUTICALS, INC. (US) | 2015-12-17 | — | — | WO | disclosed |