Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369027 | 0.88 | FOLH1 (0.48) | FOLH1CYP2C19SRCALDH1A1ALOX15 | |
| SCHEMBL17338922 | 0.85 | FOLH1 (0.44) | FOLH1SRCALDH1A1TSHRGAA | |
| SCHEMBL20522793 | 0.84 | FOLH1 (0.51) | FOLH1ALDH1A1ALOX15TSHRPOLB | |
| SCHEMBL10409409 | 0.83 | FOLH1 (0.57) | FOLH1SRCALDH1A1ALOX15TSHR | |
| SCHEMBL28743175 | 0.80 | AKR1B1 (0.52) | CYP2C19SRCPOLBEPHX1EPHX2 | |
| SCHEMBL28062032 | 0.79 | PPARG (0.49) | CYP2C19ALDH1A1POLBEPHX1P4HTM | |
| SCHEMBL22394880 | 0.79 | PPARG (0.51) | CYP2C19SRCPOLBEPHX1EPHX2 | |
| SCHEMBL28165654 | 0.79 | CYP2C19 (0.47) | CYP2C19SRCPOLBEPHX1P4HTM | |
| SCHEMBL28165655 | 0.79 | CYP2C19 (0.47) | CYP2C19SRCPOLBEPHX1P4HTM | |
| SCHEMBL7263509 | 0.77 | FOLH1 (0.48) | FOLH1SRCALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |