Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930899 | 0.86 | CCR2 (0.68) | CCR2 | |
| SCHEMBL9931228 | 0.72 | CCR2 (0.68) | CCR2 | |
| SCHEMBL9931262 | 0.72 | CCR2 (0.70) | CCR2 | |
| SCHEMBL9930876 | 0.71 | CCR2 (0.75) | CCR2 | |
| SCHEMBL9931831 | 0.71 | CCR2 (0.81) | CCR2 | |
| SCHEMBL9931202 | 0.70 | CCR2 (0.69) | CCR2 | |
| SCHEMBL9930382 | 0.67 | CCR2 (1.00) | CCR2 | |
| SCHEMBL9931396 | 0.66 | CCR2 (0.55) | CCR2TP53MAPT | |
| SCHEMBL9968188 | 0.65 | CCR2 (0.67) | CCR2 | |
| SCHEMBL9930845 | 0.64 | CCR2 (0.73) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955173-A1 | NOVEL 1,2-BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-12-16 | — | — | EP | disclosed |