Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735202 | 0.92 | PRKAA2 (0.54) | SMN1; SMN2KDM4EGAAMAPTCYP2C9 | |
| SCHEMBL1734207 | 0.92 | HRH3 (0.57) | SMN1; SMN2KDM4EGAAMAPTCYP2C9 | |
| SCHEMBL27717846 | 0.90 | PRKAA2 (0.53) | SMN1; SMN2KDM4EGAAMAPTCYP2C9 | |
| SCHEMBL1735147 | 0.88 | PRKAA2 (0.49) | SMN1; SMN2KDM4EGAAMAPTCYP2C9 | |
| SCHEMBL27717849 | 0.86 | PRKAA2 (0.49) | SMN1; SMN2KDM4EGAAMAPTCYP2C9 | |
| SCHEMBL13605399 | 0.86 | CHKA (0.55) | JAK2JAK3PTK2AXLSIGMAR1 | |
| SCHEMBL13605418 | 0.86 | CHKA (0.58) | SMN1; SMN2PRKAA2JAK2JAK3PTK2 | |
| SCHEMBL13605398 | 0.85 | AXL (0.52) | GAAPRKAA2LSSALDH1A1POLB | |
| SCHEMBL13605402 | 0.85 | ALDH1A1 (0.70) | SMN1; SMN2KDM4EGAAMAPTCYP2C9 | |
| SCHEMBL13605408 | 0.85 | ACP1 (0.57) | JAK2JAK3PTK2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-B1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2011-11-23 | — | — | EP | disclosed |