SCHEMBL17343345

SCHEMBL17343345

c1cncc(-c2cc(-c3ccncc3)cc(-c3cc(-c4ccc5ccccc5c4)nc(-c4ccc5ccccc5c4)n3)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 8/20 0.61
CYP11B1 P15538 7/20 0.61
CYP19A1 P11511 6/20 0.61
CYP17A1 P05093 4/20 0.61
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPK9 P45984 3/20 0.46
MAPK10 P53779 3/20 0.46
MAPK8 P45983 2/20 0.46
SIRT2 Q8IXJ6 2/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
CYP2A6 P11509 1/20 0.43
CYP1A2 P05177 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17343464 0.96 CYP11B2 (0.63) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL17367798 0.95 CYP11B2 (0.69) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL24252566 0.93 CYP11B2 (0.67) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL18079848 0.92 CYP11B2 (0.69) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL22534665 0.92 CYP11B2 (0.55) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL22534707 0.92 CYP11B2 (0.55) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL17343406 0.91 CYP11B2 (0.67) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL17343229 0.91 CYP11B2 (0.67) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL17343349 0.90 CYP11B2 (0.71) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL23095065 0.90 CYP11B2 (0.71) CYP11B2CYP11B1CYP19A1CYP17A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9680108-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 US disclosed
US-9680108-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
US-20150364693-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 US disclosed
US-20150364693-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 US disclosed