Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.69 |
| ▸ | FAP | Q12884 | 7/20 | 0.69 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.69 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.69 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345171 | 0.89 | PREP (0.70) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL26616429 | 0.88 | PREP (0.67) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL26616424 | 0.88 | PREP (0.67) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL24067537 | 0.82 | PREP (0.70) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL29359250 | 0.81 | PREP (1.00) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL17345172 | 0.80 | PREP (0.58) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL18806486 | 0.80 | ACE (0.57) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL13950866 | 0.80 | PREP (0.47) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL25822722 | 0.79 | PREP (0.54) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL11435575 | 0.78 | ACE (0.71) | PREPFAPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015192123-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2015-12-17 | — | — | WO | disclosed |
| WO-2015192124-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE (US) | 2015-12-17 | — | — | WO | disclosed |