Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.54 |
| ▸ | FAP | Q12884 | 7/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345293 | 0.79 | PREP (0.69) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL17345171 | 0.78 | PREP (0.70) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL24067537 | 0.71 | PREP (0.70) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL31488783 | 0.71 | MEN1 (0.56) | — | |
| SCHEMBL29359250 | 0.71 | PREP (1.00) | PREPFAPDPP8DPP9 | |
| SCHEMBL18806509 | 0.70 | PREP (0.52) | PREPFAPDPP8DPP9ELANE | |
| SCHEMBL17345172 | 0.70 | PREP (0.58) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL12950060 | 0.69 | CASP1 (0.50) | PREPFAPDPP8DPP9CASP1 | |
| SCHEMBL18806486 | 0.69 | ACE (0.57) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL11517312 | 0.69 | PREP (0.62) | PREPFAPDPP8DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154594-B1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES LLC (US) | 2023-07-19 | — | — | EP | disclosed |