SCHEMBL17345448

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21250136	0.93	STAT3 (0.48)	STAT3ALDH1A1TDP1CASP6MEN1
	SCHEMBL18691819	0.93	STAT3 (0.52)	STAT3ALDH1A1TDP1CASP6MEN1
	SCHEMBL17345515	0.91	STAT3 (0.48)	STAT3ALDH1A1TDP1CASP6MEN1
	SCHEMBL18731231	0.91	STAT3 (0.52)	STAT3ALDH1A1TDP1MEN1POLB
	SCHEMBL17345436	0.90	STAT3 (0.51)	STAT3ALDH1A1TDP1MEN1POLB
	SCHEMBL18807134	0.89	STAT3 (0.48)	STAT3ALDH1A1CASP6NPC1LMNA
	SCHEMBL18807133	0.89	STAT3 (0.48)	STAT3ALDH1A1CASP6NPC1LMNA
	SCHEMBL17345432	0.88	STAT3 (0.45)	STAT3ALDH1A1MEN1POLBMAPT
	SCHEMBL18691815	0.87	STAT3 (0.48)	STAT3ALDH1A1TDP1MEN1POLB
	SCHEMBL29448087	0.87	STAT3 (0.48)	STAT3ALDH1A1TDP1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.