SCHEMBL17345515

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18691819	0.93	STAT3 (0.52)	STAT3ALDH1A1TDP1CASP6POLB
	SCHEMBL17345448	0.91	STAT3 (0.50)	STAT3ALDH1A1TDP1CASP6POLB
	SCHEMBL21250136	0.89	STAT3 (0.48)	STAT3ALDH1A1TDP1CASP6POLB
	SCHEMBL17345540	0.89	STAT3 (0.50)	STAT3ALDH1A1MAPTHPGDKMT2A
	SCHEMBL18807114	0.88	STAT3 (0.52)	STAT3ALDH1A1POLBMEN1MAPT
	SCHEMBL17345527	0.88	STAT3 (0.49)	STAT3ALDH1A1TDP1MAPTNPC1
	SCHEMBL18807133	0.87	STAT3 (0.48)	STAT3ALDH1A1CASP6NPC1LMNA
	SCHEMBL18807134	0.87	STAT3 (0.48)	STAT3ALDH1A1CASP6NPC1LMNA
	SCHEMBL17345519	0.87	STAT3 (0.53)	STAT3ALDH1A1TDP1MEN1MAPT
	SCHEMBL18731231	0.86	STAT3 (0.52)	STAT3ALDH1A1TDP1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.