Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 4/20 | 0.30 |
| ▸ | REN | P00797 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350061 | 0.83 | CHRM3 (0.32) | CHRM3 | |
| SCHEMBL14310363 | 0.83 | CHRM3 (0.32) | CHRM3 | |
| SCHEMBL16542281 | 0.80 | — | — | |
| SCHEMBL13406669 | 0.78 | L3MBTL1 (0.39) | CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12642741 | 0.78 | L3MBTL1 (0.39) | CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13850386 | 0.78 | PARP1 (0.32) | — | |
| SCHEMBL6108591 | 0.78 | PARP1 (0.32) | — | |
| SCHEMBL2557783 | 0.77 | SCN3A (0.36) | KDM4E | |
| SCHEMBL25224878 | 0.75 | — | — | |
| SCHEMBL14234019 | 0.73 | L3MBTL1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150361163-A1 | METHODS FOR INCREASING RED BLOOD CELL LEVELS AND TREATING SICKLE-CELL DISEASE | ACCELERON PHARMA INC. | 2015-12-17 | — | — | US | disclosed |