Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY2 | Q08462 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 4/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347161 | 1.00 | ADCY2 (0.41) | ADCY2MEN1KMT2ACACNA1BAPBA1 | |
| SCHEMBL17347069 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL22898547 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL22898584 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL17347097 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL17347215 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18787389 | 0.88 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL17347160 | 0.86 | ADCY2 (0.45) | ADCY2MEN1KMT2ACACNA1BAPBA1 | |
| SCHEMBL17347156 | 0.86 | ADCY2 (0.45) | ADCY2MEN1KMT2ACACNA1BAPBA1 | |
| SCHEMBL17347392 | 0.83 | ITGAL (0.39) | ADCY2CACNA1BAPBA1NPSR1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015189265-A1 | SMALL MOLECULE LFA-1 INHIBITORS | ALLOCYTE PHARMACEUTICALS AG (CH) | 2015-12-17 | — | — | WO | disclosed |