Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CEPT1 | Q9Y6K0 | 10/20 | 0.44 |
| ▸ | CETP | P11597 | 10/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1733937 | 0.86 | CEPT1 (0.53) | CEPT1CETP | |
| SCHEMBL1734955 | 0.85 | CEPT1 (0.44) | CEPT1CETP | |
| SCHEMBL4526793 | 0.81 | CEPT1 (0.54) | ESR1ESR2CEPT1CETP | |
| SCHEMBL17512330 | 0.68 | KMT2A (0.41) | — | |
| SCHEMBL1735035 | 0.68 | CEPT1 (0.70) | CEPT1CETP | |
| SCHEMBL3681612 | 0.68 | ESR2 (0.55) | ESR1ESR2CEPT1CETP | |
| SCHEMBL4531439 | 0.68 | CEPT1 (0.68) | CEPT1CETP | |
| SCHEMBL3746100 | 0.67 | ESR2 (0.52) | ESR1ESR2CEPT1CETP | |
| SCHEMBL2837210 | 0.67 | CETP (0.50) | ESR1ESR2CEPT1CETP | |
| SCHEMBL3807420 | 0.67 | CETP (0.64) | CEPT1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954287-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110262658-A1 | PROCESS AND DEVICE FOR TREATING THE COATING OF THERMOPLASTIC RESIN CONTAINERS | ZOPPAS MATTEO | 2011-10-27 | — | — | US | disclosed |