CEPT1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1734167	0.83	19/20
SCHEMBL1734953	0.58	18/20
SCHEMBL1734818	0.82	17/20
SCHEMBL12153159	0.77	17/20
SCHEMBL1734890	0.73	17/20
SCHEMBL1734736	1.00	16/20
SCHEMBL1734924	1.00	16/20
SCHEMBL1734838	0.71	16/20
SCHEMBL1733898	1.00	15/20
SCHEMBL1736232	1.00	15/20
SCHEMBL1736259	1.00	15/20
SCHEMBL1734901	0.81	15/20
SCHEMBL1734822	0.80	15/20
SCHEMBL1734714	0.71	15/20
SCHEMBL12153125	0.60	15/20
SCHEMBL1733919	1.00	14/20
SCHEMBL1734850	1.00	14/20
SCHEMBL1734946	1.00	14/20
SCHEMBL1734933	0.79	14/20
SCHEMBL1736037	0.79	14/20

Clinical trials — most relevant to CEPT1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
NEO100 and High-Grade Meningioma	PHASE2	RECRUITING
A Clinical Trial of CNCT19 Cells in the Treatment of CD19 Positive Relapsed or Refractory Diffuse Non-Hodgkin Lymphoma	PHASE1	COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Human Requirements for the Nutrient Choline	nan	COMPLETED
Egg Intake, Metabolic Outcomes and Choline Levels	nan	RECRUITING
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children	nan	WITHDRAWN
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer	nan	UNKNOWN
Choline to Improve Malnutrition and Enhance Cognition	nan	RECRUITING
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients.	nan	COMPLETED
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients	nan	UNKNOWN
Choline Dose Ranging in Postmenopausal Women	nan	COMPLETED
Expression of SLC25A48 in Chronic Obstructive Pulmonary Disease	nan	NOT_YET_RECRUITING
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia	nan	UNKNOWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Epidemiology of Atherosclerosis	nan	COMPLETED
Choline and Brain Functioning in Postmenopausal Women	nan	COMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease.	nan	UNKNOWN
Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans	nan	COMPLETED
Study of Chediak-Higashi Syndrome	nan	RECRUITING
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes	nan	COMPLETED
Identification of a New Gene Involved in Hereditary Lipodystrophy	nan	COMPLETED
Supplemental Choline and Brain Development in Humans	nan	COMPLETED
Bipolar Disorder With Alcoholism in Han Chinese	nan	UNKNOWN
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Evaluation of Risk of hEpatocellular Carcinoma	nan	RECRUITING
Maternal Choline Supplementation and Offspring Cognition in Adolescence	nan	ENROLLING_BY_INVITATION
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a CEPT1 binder may also engage these)

Protein	Name	Similarity
Q6AXM5	—	1.000	Q6AXM5 →
Q8BGS7	—	1.000	Q8BGS7 →
Q7ZYQ3	—	1.000	Q7ZYQ3 →
Q5ZKD1	—	1.000	Q5ZKD1 →
Q28H54	—	1.000	Q28H54 →
Q66H21	—	0.992	Q66H21 →
Q8C025	—	0.990	Q8C025 →
Q1LZE6	—	0.989	Q1LZE6 →
SELENOI	Ethanolaminephosphotransferase 1	0.986	landscape →
Q17QM4	—	0.985	Q17QM4 →
Q5ZHQ5	—	0.982	Q5ZHQ5 →
Q8WUD6	—	0.982	Q8WUD6 →
Q80TA1	—	0.979	Q80TA1 →
Q4KLV1	—	0.978	Q4KLV1 →
Q5NV96	—	0.975	Q5NV96 →
Q7ZW02	—	0.975	Q7ZW02 →
CDS2	Phosphatidate cytidylyltransferase 2	0.967	landscape →
P24140	—	0.967	P24140 →
Q99L43	—	0.966	Q99L43 →
Q91XU8	—	0.966	Q91XU8 →
P42867	—	0.966	P42867 →
Q92903	—	0.964	Q92903 →
A0JNC1	—	0.964	A0JNC1 →
DPAGT1	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	0.962	landscape →
P23338	—	0.962	P23338 →
Q5EA65	—	0.960	Q5EA65 →
O35052	—	0.960	O35052 →
Q9QZ71	—	0.960	Q9QZ71 →
Q3ZBF8	—	0.960	Q3ZBF8 →
P98191	—	0.959	P98191 →