Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 10/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17348543 | 0.66 | KDM4E (0.36) | KDM4EMEN1NPC1HSP90AA1IDO1 | |
| SCHEMBL17348545 | 0.66 | BCL2 (0.44) | KDM4EMEN1NPC1HSP90AA1IDO1 | |
| SCHEMBL17348540 | 0.64 | ERN1 (0.43) | KDM4EMEN1NPC1HSP90AA1IDO1 | |
| SCHEMBL769026 | 0.64 | ERN1 (0.52) | PIM1ERN1 | |
| SCHEMBL19737877 | 0.63 | ERN1 (0.47) | KDM4EMEN1NPC1HSP90AA1IDO1 | |
| SCHEMBL28992032 | 0.62 | TRIM24 (0.50) | KDM4ERAB9APIM1ERN1 | |
| SCHEMBL4289408 | 0.62 | ERN1 (0.54) | PIM1ERN1 | |
| SCHEMBL30386098 | 0.62 | TRIM24 (0.50) | KDM4ERAB9APIM1ERN1 | |
| SCHEMBL1527084 | 0.62 | PIM1 (0.45) | PIM1ERN1 | |
| SCHEMBL30366229 | 0.62 | PIM1 (0.45) | PIM1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015191640-A2 | BICYCLIC XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE (US) | 2015-12-17 | — | — | WO | disclosed |