Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17348550 | 0.79 | ERN1 (0.47) | ERN1 | |
| SCHEMBL2339656 | 0.77 | MEN1 (0.44) | BCL2MCL1ERN1MEN1RAB9A | |
| SCHEMBL2339658 | 0.74 | MEN1 (0.47) | BCL2MCL1ERN1MEN1RAB9A | |
| SCHEMBL17348548 | 0.70 | BCL2 (0.41) | BCL2MCL1MEN1RAB9AKMT2A | |
| SCHEMBL769026 | 0.68 | ERN1 (0.52) | PIM1ERN1 | |
| SCHEMBL17348572 | 0.66 | KDM4E (0.36) | PIM1ERN1MEN1RAB9AKMT2A | |
| SCHEMBL17348543 | 0.66 | KDM4E (0.36) | PIM1ERN1MEN1RAB9AKMT2A | |
| SCHEMBL13018015 | 0.64 | PDPK1 (0.37) | BCL2MCL1ERN1MEN1RAB9A | |
| SCHEMBL29951398 | 0.64 | PNP (0.48) | PDPK1 | |
| SCHEMBL20136069 | 0.63 | KDM4E (0.44) | RAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015191640-A2 | BICYCLIC XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE (US) | 2015-12-17 | — | — | WO | disclosed |