Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537273 | 0.85 | CETP (0.73) | CETP | |
| SCHEMBL1735995 | 0.84 | CETP (1.00) | CETP | |
| SCHEMBL13676808 | 0.83 | CETP (0.82) | CETP | |
| SCHEMBL4531439 | 0.76 | CEPT1 (0.68) | CETP | |
| SCHEMBL1735035 | 0.76 | CEPT1 (0.70) | CETP | |
| SCHEMBL1734864 | 0.75 | CETP (0.82) | CETP | |
| SCHEMBL4535501 | 0.75 | CETP (1.00) | CETP | |
| SCHEMBL1734979 | 0.74 | CETP (1.00) | CETP | |
| SCHEMBL17538398 | 0.74 | CETP (0.81) | CETP | |
| SCHEMBL1734885 | 0.73 | CETP (0.82) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954287-B2 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2016-02-24 | — | — | EP | disclosed |
| US-8334290-B2 | CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2012-12-18 | — | — | US | disclosed |
| EP-1954287-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110262658-A1 | PROCESS AND DEVICE FOR TREATING THE COATING OF THERMOPLASTIC RESIN CONTAINERS | ZOPPAS MATTEO | 2011-10-27 | — | — | US | disclosed |