Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.76 |
| ▸ | CEPT1 | Q9Y6K0 | 9/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734039 | 0.91 | CETP (0.79) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL1733891 | 0.91 | CETP (0.79) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL1734926 | 0.90 | CETP (0.76) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL1735094 | 0.87 | CETP (0.73) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL13677062 | 0.87 | CETP (1.00) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL1734932 | 0.85 | CEPT1 (0.80) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL2607605 | 0.81 | CETP (0.80) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL4534132 | 0.80 | CETP (0.86) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL1736076 | 0.79 | CEPT1 (0.70) | CETPCEPT1TP53THRBMAPT | |
| SCHEMBL1734732 | 0.79 | CEPT1 (0.79) | CETPCEPT1TP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954287-B2 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2016-02-24 | — | — | EP | disclosed |
| EP-1954287-B1 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110262658-A1 | PROCESS AND DEVICE FOR TREATING THE COATING OF THERMOPLASTIC RESIN CONTAINERS | ZOPPAS MATTEO | 2011-10-27 | — | — | US | disclosed |