Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17358873 | 0.81 | CYP3A4 (0.38) | ESR1ESR2MAPTALDH1A1HPGD | |
| SCHEMBL17358880 | 0.80 | ESR1 (0.39) | ESR1ESR2MAPTALDH1A1HPGD | |
| SCHEMBL3074319 | 0.76 | ESR1 (0.34) | ESR1ESR2MAPTALDH1A1HPGD | |
| SCHEMBL17358875 | 0.73 | THRB (0.40) | MAPTALDH1A1KMT2AMAOBGAA | |
| SCHEMBL634507 | 0.71 | ESR1 (0.41) | ESR1ESR2MAPTALDH1A1HPGD | |
| SCHEMBL28500449 | 0.70 | ESR1 (0.39) | ESR1ESR2MAPTALDH1A1HPGD | |
| SCHEMBL543922 | 0.69 | NR1H2 (0.78) | ESR1ESR2MAPTALDH1A1HPGD | |
| SCHEMBL19520463 | 0.69 | HSD17B10 (0.67) | ESR1ESR2MAPTALDH1A1HPGD | |
| Diphenylsulfane SCHEMBL11499754 | 0.69 | NR1H2 (0.78) | ESR1ESR2MAPTALDH1A1HPGD | |
| Hydrogen Sulfide SCHEMBL19211583 | 0.68 | HSD17B10 (0.63) | ESR1ESR2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150368280-A1 | HIGH REFRACTIVE INDEX ACRYLIC COMPOUND AND METHOD FOR PREPARING THE SAME | SAMSUNG SDI CO., LTD. (KR) | 2015-12-24 | — | — | US | disclosed |
| US-20150368280-A1 | HIGH REFRACTIVE INDEX ACRYLIC COMPOUND AND METHOD FOR PREPARING THE SAME | SAMSUNG SDI CO., LTD. (KR) | 2015-12-24 | — | — | US | disclosed |
| US-20150368280-A1 | HIGH REFRACTIVE INDEX ACRYLIC COMPOUND AND METHOD FOR PREPARING THE SAME | SAMSUNG SDI CO., LTD. (KR) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368280-A1 | HIGH REFRACTIVE INDEX ACRYLIC COMPOUND AND METHOD FOR PREPARING THE SAME | RAD51, HRH3, C5 | ESR1 721/4885ESR2 1716/4885MAPT 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.