Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.50 |
| ▸ | CDK4 | P11802 | 5/20 | 0.50 |
| ▸ | CCND1 | P24385 | 5/20 | 0.50 |
| ▸ | CCND2 | P30279 | 5/20 | 0.50 |
| ▸ | CCND3 | P30281 | 5/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 7/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.49 |
| ▸ | WEE1 | P30291 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734414 | 0.88 | CDK4 (0.47) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL1735255 | 0.87 | CSNK2A1 (0.60) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL1735178 | 0.85 | MCHR1 (0.52) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL13605301 | 0.85 | RIPK2 (0.61) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL13605344 | 0.84 | CDK4 (0.54) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL1735257 | 0.84 | MCHR1 (0.59) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL1734406 | 0.83 | MCHR1 (0.65) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL1734426 | 0.83 | MCHR1 (0.54) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL1734211 | 0.82 | RARA (0.52) | MCHR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL4212893 | 0.82 | CYP1A2 (0.63) | CYP1A2LTA4HCYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-B1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2011-11-23 | — | — | EP | claimed |