Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 7/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | CCND2 | P30279 | 2/20 | 0.46 |
| ▸ | CCND3 | P30281 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735191 | 0.87 | RIPK2 (0.43) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL13605370 | 0.85 | HRH3 (0.52) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL1735255 | 0.84 | CSNK2A1 (0.60) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL13605346 | 0.83 | HRH3 (0.56) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL13605378 | 0.82 | MCHR1 (0.55) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL1736441 | 0.81 | MCHR1 (0.53) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL1734449 | 0.81 | MCHR1 (0.53) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL1735257 | 0.81 | MCHR1 (0.59) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL1734304 | 0.81 | MCHR1 (0.55) | HRH3MCHR1RIPK2NOD2CDK4 | |
| SCHEMBL1734488 | 0.81 | HRH3 (0.56) | HRH3JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-B1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2011-11-23 | — | — | EP | claimed |