Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | MC5R | P33032 | 2/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
| ▸ | DDX3X | O00571 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | MC1R | Q01726 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17354368 | 0.93 | MC4R (0.37) | MC4RMC5RMC3RDDX3XIMPDH2 | |
| SCHEMBL17354133 | 0.91 | KDR (0.41) | DDX3XIMPDH2KMT2AKDM4EMEN1 | |
| SCHEMBL17486587 | 0.89 | IGF1R (0.36) | MC4RMC5RMC3RKMT2AMEN1 | |
| SCHEMBL13677 | 0.88 | IDH1 (0.37) | MC4RMC5RMC3RITGB1ITGA4 | |
| SCHEMBL17354281 | 0.85 | PDCD1LG2 (0.36) | MC4RMC5RMC3RKDR | |
| SCHEMBL17354195 | 0.84 | PTGER3 (0.37) | DDX3XIMPDH2ITGB1ITGA4KDR | |
| SCHEMBL17354162 | 0.84 | KDR (0.36) | DDX3XIMPDH2KMT2AKDM4EMEN1 | |
| SCHEMBL17354138 | 0.84 | KDR (0.42) | DDX3XIMPDH2KMT2AKDM4EMEN1 | |
| SCHEMBL17354348 | 0.84 | KDR (0.37) | DDX3XIMPDH2KMT2AKDM4EMEN1 | |
| SCHEMBL17354370 | 0.83 | HDAC3 (0.36) | MC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216979-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-12-22 | — | — | US | disclosed |