Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996534 | 0.73 | POLB (0.40) | ARHTR2CHTR2BMEN1HSPA1A | |
| SCHEMBL13674815 | 0.73 | POLB (0.40) | ARHTR2CHTR2BMEN1HSPA1A | |
| SCHEMBL8996574 | 0.73 | POLB (0.40) | ARHTR2CHTR2BMEN1HSPA1A | |
| SCHEMBL1058695 | 0.69 | AR (0.40) | ARPNMTCHRNB2CHRNA4HTR2C | |
| SCHEMBL29740491 | 0.69 | AR (0.40) | ARPNMTCHRNB2CHRNA4HTR2C | |
| SCHEMBL30716841 | 0.69 | AR (0.40) | ARPNMTCHRNB2CHRNA4HTR2C | |
| SCHEMBL26989692 | 0.69 | AR (0.40) | ARPNMTCHRNB2CHRNA4HTR2C | |
| SCHEMBL17504397 | 0.69 | AR (0.40) | ARPNMTCHRNB2CHRNA4HTR2C | |
| SCHEMBL1735572 | 0.69 | CES1 (0.43) | ARHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL30346324 | 0.69 | PNMT (0.46) | PNMTCHRNB2CHRNA4HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007728-B1 | A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-11-16 | — | — | EP | claimed |
| WO-2011131370-A1 | MELT-GRANULATED FINGOLIMOD | RATIOPHARM GMBH (DE) | 2011-10-27 | — | — | WO | claimed |