Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735451 | 0.84 | AR (0.35) | ARAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL1735695 | 0.84 | AR (0.35) | ARAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL1735448 | 0.84 | AR (0.35) | ARAPOBEC3AKMT2AAPOBEC3G | |
| SCHEMBL13478819 | 0.80 | AR (0.37) | ARKMT2A | |
| SCHEMBL1735760 | 0.79 | AR (0.36) | ARKMT2A | |
| SCHEMBL1735758 | 0.79 | AR (0.36) | ARKMT2A | |
| SCHEMBL1735757 | 0.79 | AR (0.36) | ARKMT2A | |
| SCHEMBL12066676 | 0.79 | AR (0.36) | ARKMT2A | |
| SCHEMBL1735446 | 0.72 | AR (0.43) | ARKMT2A | |
| SCHEMBL1735450 | 0.72 | AR (0.43) | ARKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007728-B1 | A PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-11-16 | — | — | EP | claimed |
| WO-2011131370-A1 | MELT-GRANULATED FINGOLIMOD | RATIOPHARM GMBH (DE) | 2011-10-27 | — | — | WO | claimed |