Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923871 | 0.85 | KDM4E (0.48) | ARCYP19A1SLC22A12 | |
| SCHEMBL29437980 | 0.85 | KDM4E (0.48) | ARCYP19A1SLC22A12 | |
| SCHEMBL29437981 | 0.85 | KDM4E (0.48) | ARCYP19A1SLC22A12 | |
| SCHEMBL17354621 | 0.85 | AR (0.68) | ARCYP19A1SLC22A12 | |
| SCHEMBL17354613 | 0.83 | KDM4E (0.41) | — | |
| SCHEMBL15671656 | 0.83 | AR (0.39) | ARCYP19A1SLC22A12 | |
| SCHEMBL17354629 | 0.82 | AR (0.50) | ARCYP19A1SLC22A12 | |
| SCHEMBL17354624 | 0.81 | AR (0.49) | ARCYP19A1SLC22A12 | |
| SCHEMBL13720336 | 0.81 | MAPT (0.55) | SLC22A12 | |
| SCHEMBL29438001 | 0.81 | MAPT (0.55) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216967-B2 | Imidazolidinedione derivatives | AUTIFONY THERAPEUTICS LIMITED (GB) | 2015-12-22 | — | — | US | disclosed |